Iodine solution is widely used as a topical antiseptic in the treatment of superficial wounds. It is a highly effective method of decontaminating intact skin and minor wounds and has a low toxicity profile. Povidone-iodine preparations have replaced older iodine solutions and are now the most widely used form.

Although the treatment is considered safe, a number of recent reports of iodine toxicity in newborns receiving ongoing treatment with topical iodine-based solutions suggests that it should be used with caution as an ongoing treatment in this group and TSH monitoring considered where appropriate (Khashua 2005).

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