Antiplatelet And Anticoagulant

There have been several case reports of G. biloba causing haemorrhage during or after surgery (Hauser et al 2002, Schneider et al 2002) and there is evidence that one of its components, ginkgolide B, is a platelet-activating factor antagonist (Smith et al 1996). However, three placebo-controlled studies have failed to detect a significant effect for G. biloba on platelet function or coagulation (Bai Dit et al 2003, Jiang et al 2003, Kohler 2004). One was an escalating dose study that found that 120 mg, 240 mg or 480 mg given daily for 14 days did not alter platelet function or coagulation (Bal Dit et al 2003).

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