Antidepressant Drugs

Ginkgo biloba may reduce the sexual dysfunction side-effects of these drugs and improve sleep continuity; however, results from clinical studies are mixed — possible beneficial interaction.

VALPROATE, DILANTIN, DEPAKOTE

There is a report of two patients using valproate who experienced seizures with ginkgo use (Chavez et al 2006). There is also a report of a patient taking Dilantin and Depakote and ginkgo, together with other herbal medicines, who suffered a fatal breakthrough seizure, with no evidence of non-compliance with anticonvulsant medications (Kupiec & Raj 2005). The autopsy report revealed subtherapeutic serum levels for both anticonvulsants Depakote and Dilantin; however, it is uncertain whether effects can be attributed to ginkgo — observe patient taking ginkgo with these medicines.

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