Analgesic And Local Anaesthetic

Both the aqueous and lipid-soluble extracts of kava exhibit antinociceptive properties in experimental animal models (Jamieson & Duffield 1990). The effect is not mediated by an opiate pathway, as naloxone does not reduce the effects when administered in doses that reverse the effects of morphine. More recently, in vitro research has identified several compounds found in kava that have the ability to inhibit COX-1 and to a lesser extent COX-2 enzyme activities (Wu et al 2002).

The local anaesthetic effect of kava is well known for topical use and has been described as similar to procaine and cocaine (Mills & Bone 2000).

Drug Addiction

Drug Addiction

If you're wanting to learn about drug addiction... Then this may be the most important letter you'll ever read You Are Going To Get A In Depth Look At One Of The Most Noteworthy Guides On Drug Addiction There Is Available On The Market Today. It Doesn't Matter If You Are Just For The First Time Looking For Answers On Drug Addiction, This Guide Will Get You On The Right Track.

Get My Free Ebook


Post a comment