Agerelated Macula Degeneration

A high intake of beta-carotene-containing foods has been associated with the prevention of ARMD and observational and experimental data suggest that carotenoid supplements may delay progression of both ARMD and vision loss. This is supported by the findings from the ARED Study, an 11 -centre, double-masked clinical trial involving 3640 participants with ARMD that found supplementation with vitamin C 500 mg, vitamin E 400 IU, beta-carotene 1 5 mg and zinc 80 mg for 6 years significantly reduced the development of advanced ARMD and moderate visual acuity loss (Kassoff et al 2001). Although beta-carotene and other nutrients may have been found to be beneficial for preventing ARMD, the carotenoids lutein and zeaxanthin appear to provide the most protection (see Lutein/zeaxanthin monograph).

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