Adverse Reactions

Toxicity studies in rats fed up to 5% of their diet in LGIn showed no toxic events (Tsubuku et al 2004) and glutamine dose-response studies have demonstrated 'good tolerance without untoward clinical or biochemical effects' (Ziegler et al 1999).

Most adverse reactions are mild and uncommon; they include gastrointestinal complaints such as constipation and bloating (PDRHealth 2006a). No evidence of harm has been observed in the studies conducted to date (Wischmeyer 2003).

A report exists of mania in two hypomanic patients after self-medication with up to 4 g/day glutamine (Membane 1984). As glutamine is a pre-cursor of GABA this may provide a possible explanation.

Two cases of a transient increase in liver enzyme levels have also been reported (Hornsby-Lewis et al 1994).

Constipation Prescription

Constipation Prescription

Did you ever think feeling angry and irritable could be a symptom of constipation? A horrible fullness and pressing sharp pains against the bladders can’t help but affect your mood. Sometimes you just want everyone to leave you alone and sleep to escape the pain. It is virtually impossible to be constipated and keep a sunny disposition. Follow the steps in this guide to alleviate constipation and lead a happier healthy life.

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