Abrasions (f1; WHO); Abscess (f; CAN; DLZ); Acne (f; CRC; WHO); Acrochordons (f; CRC); Adenopathy (f; DEP); Alopecia (f; CRC; DAV; KAP); Amenorrhea (f; CRC; PH2); Anemia (f; WHO); Apoplexy (f; DEP); Arthrosis (f1; CAN; EGG; WO3); Asthma (f12; CAN; DLZ; EGG; KAP; PNC; RCP9(1); NP9(2):8); Bacteria (1; APA; PH2; NP9(2):8); Baldness (f; CRC); Bite (f; ULW); Bleeding (f; CRC); Blindness (f; WHO); Boil (f; AAB); Bronchosis (1; CAN; WO3); Bruise (f1; JFM; WHO); Bugbite (f1; APA; ULW); Burn (f1; AAB; CAN; ULW; VOD; WAM; WHO; X15751795); Cancer (f1; FNF, JAD; JLH; PH2); Cancer, anus (f1; CRC; JLH); Cancer, breast (f1; CRC; JLH); Cancer, larynx (f1; CRC; JLH); Cancer, lip (f1; CRC; JLH); Cancer, liver (f1; l CRC; JLH); Cancer, lymph (f; DEP); Cancer, nose (f1; CRC; JLH); Cancer, skin (f1; CRC; JLH); Cancer, stomach (f1; CRC; JLH; PH2); Cancer, tongue (f; EGG; JLH); Cancer, uterus (f; CRC; JLH); Cerebrosis (f; DLZ); Childbirth (f; CRC; DAA); Cholecystosis (f; JFM); Cold (f; CRC; JFM); Colic (f; DEP; KAP; PH2); Colitis (f12; JFM; X15199891; X15043514); Condyloma (f; CRC; JLH); Congestion (f; DLZ); Conjunctivosis (f; EGG; DEP; PHR); Constipation (f12; DAA; PH2; WAM; adult only); Consumption (f; KAP); Convulsion (f; CRC; NP9(2):8); Cough (f; APA; CRC; KAP); Cys-tosis (f; JFM); Decubitis (f; AAB); Dermatosis (f1; PH2; ULW; WHO; WO3; NP9(2):8); Diabetes (f1; APA; CAN; VOD; JAC7:405; NP9(2):8); Dysmenorrhea (f; AHL; KAP); Dyspepsia (f; AHL; CRC); Eczema (f; CAN; CRC); Edema (f1; CAN; JFM; VOD; WHO); Enterosis (f; CRC; VOD;
WO3); Epilepsy (f; KAP); Erysipelas (f; CRC; EGG); Erythema (f12; X15857459); Escherichia (1; NP9(2):8); Fever (f; DEP; GHA; VOD; NP9(2):8); Flu (1; NP9(2):8); Fracture (1; RCP7(1)); Frostbite (f12; APA; PH2; WHO; NP9(2):8); Fungus (1; AAB; APA; MPI; PH2); Gastrosis (f; CRC; VOD; WO3); Gingivosis (f; WO3); Glaucoma (f; WHO); Glioma (1; X15747063); Glossosis (f; JLH); Gonorrhea (f; JFM); Headache (f; GHA; VOD); Hemorrhoid (f; APA; CRC; WHO); Hepatosis (f1; BEJ; CRC; DEP; RCP6(1)); Herpes (12; AAB; PH2; NP9(2):8; RCP7(1)); High Cholesterol (1; WO3; X14598919); High Triglycerides (1; JAC7:405); HIV (1; WO3); Hysteria (f; CRC; VOD); IBD (12; X15043514); Immune Deficiency (1; CAN; PNC); Impotence (f; NP9(2):8); Indigestion (1; WAM); Infection (f1; APA; BEJ; PH2; NP9(2):8) Infertility (1; CRC; MPI); Inflammation (f1; CAN; CRC; GHA; PH2; VOD; WHO; NP9(2):8; X15182910); Intoxication (1; X8937458); Ischemia (1; PH2); Itch (f; DAA); Jaundice (f; CRC; KAB); Klebsiella (1; NP9(2):8); Leprosy (f; KAB); Leukemia (f; CRC; JLH); Leukorrhea (f; JFM); Lumbago (f; KAB); Measles (1; NP9(2):8); Mouth Sores (f1; CAN; EGG); Myalgia (f; KAB); Mycosis (1; FNF; PH2; WHO); Nephrosis (f; JFM); Ophthalmia (f; DEP; KAB); Pain (f; EGG; GHA; PH2); Peptic Ulcers (f1; CAN; CRC); Periodontosis (f; EGG); PMS (f; APA); Pneumonia (f; JFM); Proctosis (f; CRC); Pseudomonas (1; NP9(2):8); Psoriasis (f12; CAN; PH2; WHO; NP9(2):8; X15857459); Pulmonosis (f; JFM); Radiation Burns (1; CRC; DAA; WHO); Rash (f1; AAB; IED); Rheumatism (f; WO3); Ringworm (f1; APA); Salmonella (1; CRC); Seborrhea (f; WHO); Shock (1; X15566601); Snakebite (f; IED); Sore (f1; IED; X15751795); Sore Throat (f; JFM); Splenosis (f; DEP; KAB); Sprain (f; JFM); Staphylococcus (1; CRC; PH2); Sting (f; IED); Stomatosis (f; JLH); Strangury (f; KAB); Streptococcus (1; CRC); Sunburn (f1; AAB; PNC; VOD; WAM); Swelling (f; GHA; JFM); Syphilis (f; PHR); Toothache (f; DAV); Trachosis (f; WO3); Tuberculosis (1; DAA); Tumors (f1; CRC); Ulcer (f1; APA; JFM; PH2; VOD; WAM; WHO; WO3); Uterosis (f; CRC); Vaccinia (1; NP9(2):8); Vaginosis (f; APA); Venereal Disease (f; CRC; JFM); Virus (1; PH2; NP9(2):8); Wart (f; CRC; JLH); Weaning (f; VOD); Worm (f1; IED; MPI; PH2); Wound (f1; APA; CAN; CRC; NP9(2):8).
I would not myself think of it as food but TAN calls it a vegetable and FAC says the gel is often added to juices and jellies; bitter extracts are used in some beverages and candies and Dr. Samst Swedish bitters (FAC; TAN); 50-300 mg powder in a single dose at bedtime (AHP); 50-200 mg powder (APA); 1 Tbsp gel 3 x/day (APA); 25 mg in 701 mg soybean oil, 1-2 softgels 3 x/day; apply topically; or 1 tsp juice after meals (SF).
• Arabs rub fresh leaves or juice over the body to cool fevers (GHA).
• Ayurvedics regard the plant as alexiteric, alterative, anthelmintic, aphrodisiac, and useful for asthma, bronchitis, dermatitis, erysipelas, fever, hepatosis, jaundice, leprosy, ophthalmia, splenomegaly, and tumors (KAB).
• Caribbeans eat the "jelly" for constipation, cough, and sore throat (JFM).
• Chinese as early as 100 A.D. used aloe for convulsions, dermatosis, fever, and sinusosis (NP9(2):8).
• Curacaons take the sap for gallbladder ailments (JFM).
• Greeks in Dioscorides' time used the sap for boils, dermatosis, itch, sores, and took it internally for infections and stomach disorders (NP9(2):8).
• Haitians make a hot aqueous extract of dried leaves as an antidiabetic, purgative, and vermifuge (VOD).
• Jamaicans take the "jelly" in decoction for biliousness and cold (JFM).
• Kenyans taught me how to use the gel as an efficacious sunscreen (JAD).
• Latinos eat jelly-like flesh to relieve sore throat (JFM).
• Peruvians apply the gel to burns, conjunctivitis, erysipelas, inflammation, and sores (EGG).
• Trinidadans steep the flesh in stout, for jaundice; in rum, for pneumonia (JFM).
• Yucatanese apply heated leaves to abscesses, bruises, erysipelas, and gum boils (JFM).
Gel Class 1 Internally; Gel Class 2d Externally (AHP); Class 2b, 2c, 2d for the powder. Dermatosis; Diarrhea; Intestinal Cramps; Nephrosis; Ulcers. Newall, Anderson, and Phillipson caution that anthra-quinones may be purgative, and an irritant to GI tract. Because of its cathartic and reputed abortifacient actions, its use in pregnancy and lactation should be avoided. However, they suggest that topical, but not oral, application might be okay during pregnancy and lactation (CAN). The latex can be a drastic cathartic. Contraindicated for pregnant women and children (LRNP). Do not use internally in pregnancy (WAM). Do not use with undiagnosed abdominal pain (WAM). Do not use internally for more than 10 days (WAM). Epidemiological studies in Germany reveal that abusers of anthranoid laxatives have three times higher rate of colon carcinoma (AEH). May cause allergic dermatosis. Taken in excess it may result in ulcers or irritated bowels (TMA, 1996). Hypoglycemic. Commission E reports contraindications, adverse effects, and interactions of anthranoid laxatives (AEH). Naturopaths Yarnell and Meserole (1996) state that people allergic to aloe may develop a severe rash following its application. Alcoholic extract at 100 mg/kg for 3 months is toxic in mice (AAB). While not indicting this species, Neuwinger (1996) notes several fatalities from other species of Aloe. Few botanists can identify the species of aloe with nothing but the latex there, no leaf, no flower, etc. (JAD).
Aloe gel, Barbados aloe, and aloe powder contain, respectively, 4.87, 4.65, and 4.21% aloin, and 2.2, 2.1, and 2.03% aloe emodin. Gel preparations are reportedly effective against peptic ulcers (unless stress induced), radiation burns, and skin ulcers, and ineffective against stress-induced gastric and peptic ulcers. Healing wounds (10 mg/kg scu rat; 100 mg/kg scu mus); Bezakova et al. (X15751795), finding antilipoxygenase activity for aloe extracts, further rationaliz use of aloe extracts in acute inflammation, especially minor burns and skin ulcers (X15751795). Paulsen et al. (2005), in a double-blind, placebo-controlled study of commercial Aloe vera gel, found it useful in psoriasis vulgaris. In 41 patients with stable plaque psoriasis, erythema, infiltration, and desquamation decreased in 72.5% [but 82.5% improved on placebo, making it better than the aloe. Sounds like placebo and Zoloft (X15857459).]. Mijatovic et al. (2005) reported antigliomic action of aloe emodin, a chemical found in aloe and many other unrelated species. The antigliomic activity involves induction of both apoptosis and autophagy, as well as differentiation of glioma cells (X15747063). Biswas and Mukherjee (2003) proved vulnerary activity of several folkloric wound healers, including aloe, found effective in experimental models (X15866825).
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