Inhaling pollen or ingesting seeds may cause favism, an especially severe hemolytic anemia, an inherited enzymatic deficiency (glucose-6-phosphate-dehydrogenase) occasional among Mediterranean people (Greeks, Italians, Semitics). Injected intravenously in rabbits, broadbean extracts have produced hemoglobinuria and death (POB). Overdosage, especially in genetically susceptible individuals, can rapidly lead to diarrhea, queasiness, vertigo, and vomiting. In more severe cases, anuria, fever, hemoglobinuria, icterus, and/or oliguria occur. Following ingestion and digestion, pyrimidine derivatives in high doses can cause hemolysis (PHR). L-Dopa may cause a rise in blood pressure (PHR). L-Dopa is contraindicated if you have heart, liver, lung, kidney, or thyroid problems; glaucoma; or are taking vitamin B6, antidepressants (especially MAOIs), or antipsychotic drugs. L-Dopa may activate malignant melanomas, which, however, can be checked by 100 mg/day coumarin, found in the tonka bean.
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