AHP Class 1. None noted (PHR). "Health hazards or side effects following the proper administration of designated therapeutic dosages are not known" (PH2). "A very weak oxidative mutagenic action has been revealed by cumin" (X14531636). Spaniards (VAD) are more cautious but it may be generic for essential oils. Except for specified VAD indications, not for pregnant nor lactating women; not for not children less than 6 years old. Not for patients with Crohn's, epilepsy, gastritis, hepatosis, IBS, neuroses, Parkinson's, and ulcers. There is a canned contraindication that could apply to every herb: "Do not prescribe alcoholic tinctures to recovering alcoholics" (VAD).
Could the biblical cumin have prevented the diabetes in those 300 million people worldwide who have it; a leading cause of amputation, blindness, heart attack, and kidney failure among adults? Lee (2005) establishes that cuminaldehyde inhibits aldose reductase (IC50 = 0.85 ^g/ml) and alpha-glucosidase (IC50 = 500 ^g/ml). Lee (2005) optimistically champions cuminaldehyde for its antidiabetic potential (X15796577). Cuminaldehyde was half as powerful at inhibiting alpha-glucosidase as acarbose and quercetin and could serve as an antidiabetic (X15796577).
Was this article helpful?