Sources Absorption Function and Metabolism

D J McNamara, Egg Nutrition Center, Washington, DC, USA

© 2005 Elsevier Ltd. All rights reserved.

The intestinal absorption of cholesterol, its transport through the vascular system, its utilization for synthesis of steroids and bile acids, and its fecal excretion represent a complex interplay between two metabolic processes: the absorption of exogenous dietary cholesterol and endogenous cholesterol synthesis by body tissues. From the initial mixing of dietary and biliary cholesterol in the small intestine to the excretion of fecal neutral and acid steroids, there are two sources of cholesterol, which combine to determine

Gregory JR, Collins DL, Davies PSW, Hughes JM, and Clarke PC (1995) National Diet and Nutrition Survey: Children Aged J/2-4/2, pp. 27-48. London: HMSO.

Gregory J and Lowe S (2000) National Diet and Nutrition Survey: Young People Aged 4 to 18 Years, Volume 1: Report of the Diet and Nutrition Survey, pp. 45-105. London: HMSO.

Prasad AS, Miale A, Farid Z, Schulert A, and Sandstead HH (1963) Zinc metabolism in patients with iron deficiency anaemia, hypogonadism and dwarfism. Journal of Laboratory and Clinical Medicine 61: 537-549.

Rayner PH and Rudd BT (1973) Emotional deprivation in three siblings associated with functional pituitary growth hormone deficiency. Australian Paediatric Journal 9: 79-84.

Rowe KS and Rowe KJ (1994) Synthetic food coloring and behavior: a dose response effect in a double blind, placebo controlled, repeated measure study. Journal of Pediatrics 125: 691-698.

WHO (1972) Nutritional Anemia. WHO Technical Report Series Number 3. Geneva: WHO.

the overall dynamics of whole-body cholesterol metabolism and the ability of the metabolic regulatory processes to maintain tissue cholesterol homeostasis as well as a steady-state plasma cholesterol level. It is the balance between dietary cholesterol intake and absorption, endogenous cholesterol synthesis, and fecal steroid excretion that determine overall cholesterol homeostasis in the body (Table 1).

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