The true secondary hyperparathyroidism of chronic renal failure (CRF) has been extremely difficult to treat by clinicians because of high Pi and PTH concentrations in this condition. Traditional treatment includes the use of binders (chemical) to prevent Pi absorption from the small intestine. In recent years, a calcium-sensing receptor (CaR) in the parathyroid glands has been identified and drugs are being developed that will trick the CaR into thinking that serum calcium is normal rather than depressed, thereby reducing PTH secretion. A reduction in PTH then helps in the conservation of bone tissue since bone loss is such a severe problem in CRF patients.
Was this article helpful?
A Hard Hitting, Powerhouse E-book That Is Guaranteed To Change The Way You Look At Your Health And Wellness... Forever. Everything You Know About Health And Wellness Is Going To Change, Discover How You Can Enjoy Great Health Without Going Through Extreme Workouts Or Horrendous Diets.