Osteopetroses are a class of rare genetic disorders characterized by defective osteoclast function and a consequent failure of bone remodeling. Symptoms vary with severity but may include skeletal malformation with dense but fragile bones. Recurrent infection and spontaneous bleeding may result from the crowding out of the marrow cavity by unresorbed bone and mineralized cartilage.

See also: Body Composition. Calcium. Carbohydrates: Regulation of Metabolism. Glucose: Metabolism and Maintenance of Blood Glucose Level.

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