Nutritional Effects on Phospholipid Molecular Species

Practically all nutritional studies of dietary lipid effects on cellular phospholipid compositions have reported fatty acid compositions, with no molecular information. Due to significant differences in the detailed regulation of their phospholipid composition and metabolism, nutritional data obtained from laboratory animals generally have only a restricted application to human nutrition. The data in Figure 6 are from one study in which human volunteers were fed fish oil supplements for 4 weeks and the change in their erythrocyte PE molecular species composition was measured. Of interest, the extent of increase in species containing

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