Introduction

In the next article, a cofactor is defined as any nonenzyme component that promotes the catalytic prowess of an enzyme. The definition emphasizes function rather than structure. Since nearly a third of all enzymes require metal ions for catalytic function, it is apparent that inorganic components make up a substantial number of cofactors. Most of the trace metals have a common denominator in their intimate involvement with enzymes. Many are active site components that bind substrates, accept electrons, stabilize tertiary and quaternary structures, or even regulate the pace of metabolic pathways. In this article, the individual metal ion cofactors are discussed.

Breaking Bulimia

Breaking Bulimia

We have all been there: turning to the refrigerator if feeling lonely or bored or indulging in seconds or thirds if strained. But if you suffer from bulimia, the from time to time urge to overeat is more like an obsession.

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