Histidine is the precursor for histamine, which is important for the immune system by mediating growth and functionality of immune cells. Excessive release of histamine from mast cells induces the clinical signs of allergy (dilation of capillaries and larger blood vessels, increased capillary permeability and swelling, itching, and anaphylactic shock). These phenomena are effected via the Hj receptor, which is found in smooth muscle cells of the vascular wall and bronchi, among others. Furthermore, histamine acts as a neurotransmitter and mediates gastric acid production. The latter occurs via the H2 receptor found in gastric mucosa. There is no literature available on the potential relationship between histidine availability and histamine production and action.

Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

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