Effects on the Gastrointestinal System

Caffeine relaxes smooth muscle of the biliary and gastrointestinal tracts and has a weak effect on peristalsis. However, high doses can produce biphasic responses, with an initial contraction followed by relaxation. Caffeine seems to have no effect on the lower oesophageal sphincter. The increase in both gastric and pepsin secretions is linearly related to the plasma levels obtained after the administration of a dose of 4-8mgkg~1. In the small intestine, caffeine modifies the fluid exchange from a net absorption to a net excretion of water and sodium.

The role of caffeine in the pathogenesis of peptic ulcer and gastrointestinal complaints remains unclear, and no association has been found in clinical and epidemiological studies.

Supplements For Diabetics

Supplements For Diabetics

All you need is a proper diet of fresh fruits and vegetables and get plenty of exercise and you'll be fine. Ever heard those words from your doctor? If that's all heshe recommends then you're missing out an important ingredient for health that he's not telling you. Fact is that you can adhere to the strictest diet, watch everything you eat and get the exercise of amarathon runner and still come down with diabetic complications. Diet, exercise and standard drug treatments simply aren't enough to help keep your diabetes under control.

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