Feillet Coudray and Y Rayssiguier National

Institute for Agricultural Research, Clermont-Ferrand,

France

© 2005 Elsevier Ltd. All rights reserved.

Magnesium (Mg), the second intracellular cation after sodium, is a essential mineral. It is a critical cofactor in more than 300 enzymatic reactions. It may be required for substrate formation (Mg-ATP) and enzyme activation. It is critical for a great number of cellular functions, including oxidative phosphorylation, glycolysis, DNA transcription, and protein synthesis. It is involved in ion currents and membrane stabilization. Mg deficiency may be implicated in various metabolic disorders, including cardiovascular diseases, immune dysfunction and free radical damage.

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