Hot Flash Remedy report

Hot Flash Remedy report

Heres what youll discover in The Hot Flash Remedy report: The herb from central Asia that can stop hot flashes in one week! (page 17) How your brain gets tricked into firing up the furnace and how to recalibrate it. (page 6) 7 lifestyle factors that increase your odds of suffering from hot flashes. (page 19) 9 food items that bring hot flashes on fast and furious! (page 10) The bean that actually makes hot flashes non-existent for women in other countries. (page 12) The secret ingredient in your fruit bowl that extinguishes the flame. (page 17) Why 6 meals a day are better than 3 and eating more often wont make you gain weight! (page 10) How common wildflowers hold the key to shutting down hot flashes. (page 16)

Hot Flash Remedy report Overview

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Black Cohosh Cimicifuga Racemosa

Black cohosh is a plant native to North America that has traditionally been used by Native Americans for a number of gynecological conditions. Its modern use has been predominantly for treatment of menopausal symptoms such as hot flashes. The active ingredients in black cohosh have yet to be identified. The estrogenic isoflavone formononetin was thought to be partially responsible for its actions however, this isoflavone has recently been shown to be entirely absent in some black cohosh products (2). The mechanism of action of black cohosh also remains unknown. Although it was initially thought to activate estrogen receptors, recent studies regarding its estrogenic properties have been conflicting (3,4). A recent review of alternative therapies for menopausal symptoms identified three randomized, controlled clinical trials in favor of black cohosh (5). These studies contained small sample sizes and were of short duration (6 months or less). One trial of black cohosh on hot flashes in...

Overactive metabolism

Symptoms Staring eyes (exophthalmos) and a distressed expression on the face, which may be swollen. The skin and hair are usually dry. There may be vertigo, with hot flashes, fainting, and throbbing head pain with a rush of blood to the head. Other symptoms include an increased appetite yet a noticeable weight loss (see right) and

Table 61 Some Experts Recommendations on CAM Therapies

Improve sleep, relieve pain, and diminish symptoms of anxiety or depression. Some CAM therapies can help with treatment-related side effects, such as nausea or hot flashes. In some instances, they may also improve immune function. For example, studies have shown benefit from hypnosis for cancer pain and nausea from relaxation therapy, music therapy, and massage for anxiety and from acupuncture for nausea and pain.

Female Reproductive System Disorders

Menopausal hot flushes According to one randomised, double-blind placebo-controlled study EPO supplementation significantly reduces the maximum number of night-time flushes, although other symptoms failed to respond. The study used a dose of four capsules daily (each containing 500 mg EPO and 10 mg vitamin E) over 6 months (Chenoy et al 1994).

Symptom Control Quality of Life Survivorship

Cooperative group trials have also addressed complex questions regarding symptom control and quality of life in patients receiving therapy or palliative care. Quality of life scores have been used to determine if control of symptoms - pain, fatigue, nausea, anorexia and cachexia, chemotherapy-related anemia, depression, hot flashes - translates to an improvement in quality of life. For example, contrary to anecdotal reports and some small studies, results of a North Central Cancer Treatment Group Study suggested that megestrol acetate is superior to dronabinol for the treatment of cancer-associated anorexia and or weight loss.47 Companion studies to treatment trials, such as those evaluating 5-azacitidine, have also prospectively analyzed the impact of therapy on quality of life.48 As recently reviewed, a growing body of literature, including seminal research from Cooperative Group trials,49'50, has examined the physical, mental, and emotional sequelae of cancer treatment on long-term...

Hormonally Mediated Events

Menopause may cause uncomfortable symptoms in many women and can be controlled to a great extent by HRT. Some of these symptoms, hot flashes, fatigue, and bone thinning (leading to osteoporosis) can intensify symptoms and problems related to MS. Osteoporosis has been linked to the treatment of MS with steroids, and this condition may worsen during the peri-menopausal or menopausal state of life.

Edible Plants and Phytochemicals

In vitro studies show conflicting effects. On the one hand, soy isoflavones induce apoptosis of many types of cancer cells on the other hand, estrogen receptor-bearing human breast cancer cells proliferate in tissue culture when exposed to isoflavones. Although the widespread use of soy in Asia is cited in support of the safety of soy foods, the intake of isoflavones among Asian women consuming soy regularly is in the range of 15-40 mgday-1, significantly less than the isofla-vone content of a serving of soymilk as consumed in the US. In clinical trials, soy isoflavones have not been effective in relieving hot flashes of menopausal women but do diminish the increased bone resorption that causes postmenopausal bone loss. In pre-menopausal women, soy isoflavones may cause menstrual irregularities. The successful development of soy derivatives as functional foods will require that these complex and diverse effects of different soy components in different clinical settings be...

Clinical phase II studies of IAS

Because it became increasingly clear that the time to androgen-independence seems not to be prolonged by IAS, trials focussed on the impact of the intermittent therapy on side effects of AS and QoL. Malone et al estimated that approximately 50 of patients recovered from anaemia during off-therapy periods and that the weight gain normally associated with CAS was prevented 25 . Bouchot et al reported hot flushes in most cases during the on-therapy period, which showed significant improvement during treatment cessation periods and pain

Table 112 Symptoms of Anxiety

Often a number of factors occur simultaneously and contribute to a person's emotional crisis. One of my patients is a woman in her late forties who is raising two teenage children. Several years ago she was diagnosed with breast cancer and underwent a lumpectomy and radiation treatment. More recently, she had a local recurrence of her cancer and opted for a mastectomy followed by reconstructive surgery and then chemotherapy. When I first saw her, there was no single reason for her depression. She was stressed over the teenage rebellion going on in her home. Sleep was difficult because of uncontrolled hot flashes, a result of premature menopause that was induced by the chemotherapy, and

Menopausal Symptoms

The natural oestrogen-receptor activity of soy is popularly considered an alternative to controversial HRT for postmenopausal women (Sliva 2005). A recent analysis of 17 trials, however, found mixed results for the effects of soy isoflavone extracts on menopausal symptoms (Nelson et al 2006). Although some data seem to support the efficacy of isoflavones in reducing the incidence and severity of hot flushes, many studies have not found any difference between the isoflavone recipients and the controls. Inadequate data exist to evaluate the effect of isoflavones on bone mass and vaginal dryness (Greenwood et al 2000).

Select the points according to a given medical diagnosis and consider them as having a pseudopharmacological activity

In the patient in Figure 10.5 the main symptom prompting consultation with the acupuncturist was tiresome hot flushes in menopause. Secondary symptoms were neck stiffness, constipation and hemorrhoids. Seven tender points were identified with PPT (Fig. 10.5A). The selection of points in the first session was directed particularly on the areas commonly related to a climacteric syndrome the antitragus and the fossa ovalis. Two points were selected on the antitragus one within the genital or gonadotropinic area of Nogier, corresponding to the Chinese forehead area (AT1 e), the second on the lower part of the antitragus within the area of dysthymia and depression, corresponding to the French hypothalamus and Chinese temple (AT2 nie). One tender point was selected on the fossa triangularis, within the area which was recently considered to be related to the ovary (see Fig. 5.48). The rationale for treating hot flushes with these three points (Fig. 10.5B) was to try, from a...

Adverse Effects And Reactions Allergies And Toxicity

In the study by Welty and colleagues (2007b), of the 82 subjects who were enrolled in the study, 22 (25 ) dropped out. Reasons for dropouts included flatulence and bloating (three), constipation (one), teeth problems (one), intolerable hot flashes when off HRT or soy (four), not wanting to be off soy in control arm (one), and weight gain (one).

Presentday Cultivation And Usage

Sunflower seeds are used for the production of SO, which is a very useful dietary supplement, being enriched in fatty acids and used as an ingredient in many pharmaceutical preparations. Seeds can be sprinkled over cereals, salads, and soups, and mixed with vegetables and snacks. The seeds are diuretic and expectorant, and are now highly valued for the treatment of bronchial, laryngeal and pulmonary infections, coughs, and colds. They are also used to reduce the risk of colon cancer, the severity of hot flushes in women going through menopause, and also diabetic complications. They are also prescribed for snake bite and scorpion sting. Sunflower seed oil is used internally to alleviate constipation, as a lubricant, and is used externally as a massage oil, an oil dressing, and in the treatment of skin lesions, psoriasis, and rheumatism. The oil-cake is a valuable food for cattle and poultry (Bruneton, 1999 The Wealth of India, 2001 LaGow, 2004 Chopra et al., 2006). The oil is used in...

Linda A Jacobs Jane Alavi Angela DeMichele Steven Palmer Carrie Stricker and David Vaughn

Shortness of breath High cholesterol Forgetfulness Trouble concentration Trouble with calculations Rapid heart rate Chest pain Tightness in your chest Arm swelling side of your surgery Hand swelling side of your surgery Broken bones Bone pain Urinary frequency Burning when urinating Urine leakage when coughing Numbness tingling in hands Numbness tingling in feet Hot flashes Night sweats Vaginal dryness Decreased desire for sex Decreased satisfaction with sex Ringing in your ears Decreased hearing Weight gain (more than 10 lbs) Weight loss (more than 10 lbs)

Clinical phase III studies of IAS

This Intergroup randomized phase III trial compared IAS vs. CAS to test for non-inferiority of IAS with respect to OS. Patients had rising PSA > 3.0 ng ml > 1 year post radical radiotherapy (RRT), either initial or salvage, for localized prostate cancer. Stratification factors were time since RRT (> 1-3 vs > 3 years), initial PSA (< 15 vs > 15), prior radical prostatectomy and prior AS. IAS was delivered for 8 months in each cycle with restart when PSA reached > 10 ng ml off-treatment. Primary endpoint was OS, secondary endpoints included time to hormone refractory state, QoL, duration of treatment non-treatment intervals, time to testosterone and potency recovery. The trial was halted after a planned interim analysis demonstrated that a prespecified stopping boundary for non-inferiority was crossed. 1,386 patients were randomized to IAS (690) or CAS (696) arms. IAS patients completed a median of 2 x 8 months cycles (range 1-9) and median follow-up was 6.9 years. 524...

Is hormone replacement therapy HRT good for PD

Estrogen replacement can relieve hot flashes, which in some people can be debilitating. This is of concern to women with PD, whose risk for osteoporosis is At menopause, women stop making estrogen, and for years have been prescribed an estrogen made from the urine of pregnant horses (Premarin) and progestin, a synthetic form of the hormone progesterone (Provera). The combination is called Prempro. The treatment was originally given to relieve such symptoms as hot flashes, but later to reduce bone thinning and heart disease. Estrogen alone relieved symptoms but produced a small increase in the risk for cancer of the uterus), so the synthetic progestin was added to lower this risk. But did estrogen or an estrogen-progestin combination really reduce the risk of heart disease Two studies cast doubt on the safety of both estrogen and estrogen-progestin therapies. However, many doctors do not think the results of these studies are a reason to stop HRT. decreases risk for colorectal cancer,...

Being Prepared The Side Ef fects o f Treatm ent

Menopause is different for each woman. Symptoms can include hot flashes, vaginal dryness, decreased libido (interest in sex), urinary incontinence (leaking some urine when you cough or sneeze), or memory problems. Other health effects include an increased risk of heart disease and strokes and loss of bone strength.

Dopaminergic

It Is suggested that the effects of A. racemosa may be due to dopaminergic activity, because black cohosh extract BNO 1055 displayed dopaminergic activity with a D(2)-receptor assay (Jarry et al 2003). Considering that dopaminergic drugs reduce some symptoms (e.g. hot flushes) associated with menopause, this theory is feasible however, further studies are required to explain why black cohosh is devoid of the typical side-effects associated with dopaminergic drugs (Borelli & Ernst 2002).

Systemic Therapy

Chemotherapy, particularly alkylating agents like cyclophosphamide, can induce infertility and, in women, premature menopause, with its attendant problems of hot flashes, mood swings, vaginal dryness, and urinary incontinence. Cyclophosphamide is commonly used in breast cancer, but management of the menopausal symptoms is complicated by the fact that hormone replacement therapy is considered contraindi-cated in patients with a history of breast cancer. Consequently, other treatments must be used for hot flashes, such as antidepressants.52 This example illustrates the importance of both recognizing the symptoms related to ovarian failure in a cancer patient in which it would be otherwise unexpected, and having knowledge of the oncologic considerations of the therapies being chosen.

Other therapies

Hormone therapy plays a central role in the treatment of a number of common cancers, for example breast and prostate. Considering that this form of therapy is increasingly being given as an adjuvant and preventative agent, it is desirable that they are well tolerated and convenient. It is startling that little is known about the experiences of daily life and life quality in the men and women who receive these therapies. However, there is growing recognition that clinicians tend to underestimate the impact of side-effects of hormone therapy (Denton 1996). Research highlights that there are discrepancies between the perceptions patients and clinicians hold in terms of the level of distress caused by side-effects, and the impact such distress has on increasing the likelihood that patients will seek a change in therapy (Leonard et al. 1996). Lethargy and lack of energy feature as one of the most troublesome symptoms in this respect (Leonard et al. 1996). The Working Group on Living with...

Treatment of Fatigue

Survivors face which contribute to fatigue. These problems, once identified, are usually easily resolved. Cancer treatments that cause hormonal fluctuations may lead to insomnia. So, for example, women with breast or endometrial cancer and men with prostate cancer may be affected by hot flashes, which can keep them awake at night. The cancer treatment may need to be continued, in order to alter the estrogen or testosterone levels, despite this bothersome side effect. However, medications that don't affect these hormones may work to decrease the incidence and intensity of the hot flashes (for example, the antidepres-sant medication Effexor venlafaxine has been shown to relieve hot flashes in women with breast cancer).

Discussion

Twenty years ago it was expected that the IAS regimen would be associated with extended survival, mainly through postponing the castration-resistant status 70 . The expected associated benefits were a decrease in the adverse effects of castration, such as hot flushes, decreased libido and erection, bone and muscle problems, depression, and metabolic syndrome (Table 3). Regarding the expected QoL and adverse effects benefits, few prospective data from randomized trials are available comparing IAS to CAS treatment. The report from Salonen et al. shows some benefit in QoL for activity limitation, physical capacity, and sexual functioning 41,42 . Surprisingly, no difference was observed in drug-induced adverse effects, such as hot flushes or night sweats. This lack of a clear sexual benefit is disappointing and a little different from what is observed in other trials, especially the South European Urooncological Group or the Miller trial 13,37 . The different questionnaires might partly...

Menopause

Menopause is a natural life transition for women and usually occurs between the ages of 45 and 55. Hormonal changes result in a decline of estrogen and some women experience symptoms such as hot flashes, mood swings, and vaginal dryness. These changes may begin 4 to 6 years before the cessation of menstruation. Low-dose estrogen creams are effective for vaginal dryness. Antihistamines, diuretics, caffeine, and alcohol have a tendency to dry mucous membranes including those in the vagina. Regular exercise reduces hot flashes and other meno-pausal symptoms.

Summary

Although licorice has been known to be a useful medicinal plant for the past 3000 years, it is still luring investigators to explore new medicinal properties of this plant. In a separate chapter, Aviram et al. review the therapeutic effects of licorice extract and its major antioxidant constituents of glabridin on atherosclerosis via inhibition of the LDL oxidation molecular mechanism. The second part of the chapter reviews the potential of licorice extract and its constituents as HRT for postmenopausal women. The licorice extract and its constituents were found to bind to estrogen receptors, affect endothelial and smooth muscle cells known to have a role in cardiovascular diseases, inhibit a decrease in bone mass, affect the expression of estrogen receptors a and h, and inhibit serotonin reuptake, which may be beneficial for reducing postmenopausal hot flashes and depression. In the last part of the chapter, the depig-

Sleep and Fatigue

The importance of sleep and the treatment of sleep disturbance during and after cancer treatment have been relatively overlooked, although the area is beginning to receive more attention.17,18 In one study, over half of a sample of women with breast cancer reported symptoms of insomnia and 19 met the criteria for clinical insomnia.19 Furthermore, 58 of the patients attributed cancer as the cause of or aggravating their sleep difficulties. These prevalence rates are double those in the general population, with insomnia rates ranging from 9 to 12 . Other research has found similarly high rates of sleep disturbance in cancer patients, ranging from 45 20 to 75 ,21 depending on the sample and method of assessing sleep disturbance. A study comparing breast cancer survivors with hot flashes to healthy matched control women found that sleep disturbance rates were high in both groups (73 of cancer survivors and 67 of matched controls), but survivors had a shorter duration of sleep.22 Once...

Sleep Aging

Hot flashes aside, complaints about sleep are one of the biggest problems reported by menopausal women, says Carrier. Yet there are very few objective studies that try to understand why women have so many problems falling and staying asleep during menopause. Natural Prescription for Health Hot flashes respond to a source of organic iodine. Men and women would do well to increase protein during the day to assist the body in having enough sleep-inducing tryptophan.

The Etiology of PMS

The existence of subgroups of PMS of varying etiology may account for clinical observations that some women with severe premenstrual depression report, paradoxically, a worsening of symptoms during progesterone treatment. Indeed, such women have been reported to respond to oestrogen treatment. Their condition may be linked to progesterone excess, which has been suggested to occur in some women who experience PMS symptoms at midcycle. High luteal progesterone levels may lead to depletion of oestrogen receptors of the hypothalamus, which is consequently less sensitive to oestrogen, requiring a higher midcycle oestrogen surge for normal pituitary response. This is followed by an abrupt and pronounced oestrogen drop at midcycle which may even result in symptoms of hot flushes.

Use red clover for

Red clover's ability to alleviate menopausal symptoms is related to its flavonoid content. Flavonoids are estrogen-like plant chemicals (or phyto-estrogens) that help maintain normal estrogen levels during menopause, providing relief for hot flashes. However, red clover is safe to use and beneficial in cases of breast cancer because it reduces high estrogen levels (see box on right). Dose 3 or 4 cups a day. Can be taken by children. For chronic toxicity, constipation and skin problems this tea needs to be taken consistently over a period of five or six weeks, as the effect is cumulative. To help with hot flashes, it is best drunk cold at the first onset of a flash. hot flashes