Antibacterial Effect

Thirteen phenolic glycosides including six new compounds were isolated from seeds of C. tora. The structures of the new compounds, rubrofusarin trigluco-side, nor-rubrofusarin gentiobioside, demethylflavasperone gentiobioside, torachrysone gentiobioside, torachrysone tetraglucoside, and torachrysone apioglucoside, were deduced on the basis of spectroscopic and chemical evidence. The effect of the phenolic glycosides, their aglycones, and several other compounds structurally related to the on Escherichia coli K12, Pseudomonas aeruginosa PAO1, and some strains of Staphylococcus aureus were then examined. Among them, torachrysone, toralactone, aloe-emodin, rhein, and emodin showed noticeable antibacterial effects on four strains of meth-icillin-resistant Staph. aureus with a minimum inhibitory concentration of 2-64 Ag/mL. On the other hand, the phenolic compounds tested did not show strong antibacterial effects on E. coli and Ps. aeruginosa (14).

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