M Proanthocyanidins

Procyanidins or proanthocyanidins are oligomeric flavan-3-ol flavonoids, which occur in high amounts in some Western diets owing to their presence in cocoa/chocolate, red wine, and also in some supplements such as grape seed extract. Because they are oligomers, a number of different compounds are found naturally, consisting of either eipcatechin or catechin monomers linked in different ways with a degree of polymerization of 2-6 and more. Analytical limitations make it difficult to obtain pure oligomers above 6. Although procyanidins are only poorly bioavailable, they exert a number of effects in vivo although not specifically on the gut.

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