A blister should not be disturbed but should be left to heal on its own. It may be pierced at the edge using a sterile needle, allowing the fluid to slowly seep out. However, a blister should never be unroofed, as the top flap of skin protects against infection. Children with large, troublesome, or unexplained blisters should be seen by a doctor.

To protect the blister, a moleskin pad (available at drug stores) can be cut to resemble a doughnut, with the blister in the middle; the moleskin will absorb the friction of daily activity.

If a blister inadvertently bursts or gets pierced, the skin should not be removed over the top. Left intact even after the blister has drained, this skin flap will act as a type of bandage; it will eventually harden and fall off by itself.

Triple topical antibiotics (such as Neosporin) may eliminate bacterial contamination, but iodine or camphor-phenol will slow down healing.

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