Pyloric stenosis is a medical emergency that requires immediate surgical treatment with a pyloromyotomy, in which the thickened muscles of the pylorus are cut, relieving the obstruction. The surgery is performed with general anesthesia and lasts about an hour.

Any dehydration or electrolyte problems in the blood will be corrected with intravenous fluids. After surgery, most babies are able to eat normally very soon, usually feeding again three to four hours after surgery. However, because of swelling at the surgery site, the baby may still vomit a bit for a day or so after surgery. As long as there are no complications, most babies who have undergone pyloromyotomy can return to a normal feeding schedule and be sent home within 48 hours of the surgery. The condition does not usually recur after a complete pyloromyotomy.

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