Testing for Birth Defects

The March of Dimes believes that every state should require testing for at least these 10 disorders:

• medium-chain acyl-coa dehydrogenase (M-CAD) deficiency (Incidence: 1 in 15,000)

• congenital hypothyroidism (1 in 4,000)

• congenital adrenal hyperplasia (CAH) (1 in 5,000)

• biotinidase deficiency (1 in 70,000)

• maple syrup urine disease (1 in 250,000)

• sickle cell anemia (1 in 400 among African-Americans; 1 in 1,000-30,000 among Hispanics)

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