said depression is common among acne patients, whether or not they take isotretinoin. It appears that patients who are prone to depression may be at higher risk for developing depression while taking isotretinoin.

other side effects may include thinning hair, itching, dry and flaky skin, occasional aching muscles, and, rarely, liver damage.

itching That familiar tickling sensation on the skin is the most prominent symptom in many skin diseases and allergies. Skin that is too dry and scaly commonly causes itching as well, and many drug reactions result in itching (especially reactions to codeine and some antibiotics). Some types of rough clothing, soap, and detergents can trigger an itching response in some sensitive children.

In addition, a wide range of disorders produce itching, including hives, eczema, fungal infections, and psoriasis. Itching all over the body may be caused by diabetes mellitus, kidney failure, jaundice, thyroid problems, or blood disorders. Anal itching in children is usually caused by worms, although it also may be caused by an anal fissure or persistent diarrhea, or by too-rough cleansing after defecation. Infestations of lice or scabies, or insect bites, can cause severe itching. Itching around the vulva may be caused by a yeast infection or hormonal changes at puberty.


Specific treatment of itching depends on the underlying cause, but in general cooling lotions such as calamine can ease the itch and irritation of the skin. Emollients can reduce skin drying and ease itching for those with dry skin. Soothing lukewarm baths in colloidal oatmeal or Aveeno bath can ease the itch caused by hives or skin rashes such as chicken pox or poison ivy.

Because soap can irritate itchy skin, especially if the skin is dry or has a rash, it should be used only when really necessary. Mild cleansing solutions or water alone may be enough to keep itchy skin clean.

While scratching can temporarily ease an itch, it can actually make itching worse over time by overstimulation. The urge to scratch can be suppressed by using lotions or salves or by applying cool wet compresses to the affected area. Systemic medications such as antihistamines also can be effective.

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