in children, complications may include bacterial infection and, rarely, reye's syndrome or encephalitis (an inflammation of the brain). Immuno-compromised patients who are susceptible to vzv are at high risk for having severe varicella infections with widespread lesions.

Between 40 and 200 people die every year in the United States due to vzv infections; half are previously healthy people and the other half are those with impaired immune systems. Death occurs more often in adults than children.

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