Pathophysiology Of The Small Bowel

The presence of pathological conditions in the small intestine can affect absorption of nutrients of the affected region. It is therefore important to consider the location of the disease to understand fully the impact it can have upon nutrient absorption. Duodenal disease may result in deficiencies of calcium and iron, whereas a diseased jejunum can reduce absorption of fats, carbohydrates and proteins. Vitamin B12 deficiency and bile acid malabsorption can result in ileal disease.

Important pathological conditions of the small intestine that will be considered in this section include duodenal ulcer disease, bacterial and viral infections, Crohn's disease, vitamin B12 deficiency, small bowel carcinomas and malabsorptive conditions, including coeliac disease.

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