Investigation of peptic ulcer

Diagnosis can be made by double-contrast barium meal examination or by endoscopic investigation. Endoscopy is the preferred investigation because it is more accurate and has the enormous advantage that suspicious lesions and HP status can be concurrently evaluated by biopsy. For those with a duodenal ulcer seen at barium meal, urea breath testing will accurately define the HP

status. In gastric ulcer disease endoscopy must be repeated after suitable treatment to confirm that the ulcer has healed.

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