Control of absorption in the small intestine

Various factors are involved in the control of water and electrolyte absorption by the cells near the tip of the villi. These include endocrine, paracrine and nervous influences. Glucocorticoids stimulate electrolyte and water absorption in both the small and large intestines. Somatostatin stimulates electrolyte and water absorption in the ileum. Absorption can be inhibited by inflammatory mediators such as histamine and prostaglandins, which are released from cells of the gastrointestinal immune system.

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