Gallbladder Disease

Cynthia W. Ko, MD, MS Guest Editor

Gallbladder diseases, particularly gallstone-related syndromes, are common clinical problems facing practicing gastroenterologists and surgeons. Our understanding of the pathogenesis of gallbladder disease, including gallstones, acalculous cholecystitis, gallbladder dysmotility, and gallbladder cancer, continues to advance at a rapid pace. Furthermore, our ability to diagnose and treat gallbladder diseases is rapidly evolving.

In this issue, recognized experts discuss recent advances in the epidemiology; pathogenesis; and endoscopic, surgical, and medical therapies for gallstones. Additional articles address evolving methods to image the gallbladder, including computed tomography, magnetic resonance imaging, and endoscopic ultrasound. Finally, articles address other important but less well-understood gallbladder diseases, covering the epidemiology, diagnosis, and management of gallbladder cancer and polyps, acalculous cholecystitis, and dysmotility.

I hope the articles in this issue provide a balanced, state-of-the-art review of current knowledge and issues in management of gallbladder diseases and stimulate further research and investigation into their pathogenesis and treatment.

I am grateful for the enthusiasm and fine contributions of each of the authors. I also extend my sincere gratitude to Kerry Holland and her editorial staff at Elsevier for their assistance.

Cynthia W. Ko, MD, MS Department of Medicine Division of Gastroenterology University of Washington Seattle, WA, USA

E-mail address: [email protected]

Gastroenterol Clin N Am 39 (2010) xiii doi:10.1016/j.gtc.2010.02.013

0889-8553/10/$ - see front matter © 2010 Elsevier Inc. All rights reserved.

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