Acute Cholecystitis

Cholcytitis

Acute cholecystitis results from obstruction of the gallbladder neck or cystic duct by a gallstone in 80 to 95 of patients.34 Acute acalculous cholecystitis (AAC) composes 5 to 15 of cases of acute cholecystitis and is typically caused by diminished gallbladder emptying (eg, in patients with severe trauma surgery, burns, shock, anesthesia, diabetes) by decreased blood flow in the cystic artery because of obstruction, hypotension, or embolization or by bacterial infection.35,36 Although most...

Guidelines For Management Of Gallstone Disease

Gall Bladder

Gallbladder stones are frequently found in asymptomatic patients during routine abdominal ultrasonography, because in most cases (60 -80 ) gallstones do not generate symptoms.43,48,49 Previous observations have shown that the average risk of developing symptomatic gallstones is 2.0 to 2.6 per year.45,50 By contrast, the presence of microstones and sludge in the gallbladder is a major risk factor for the development of biliary pain and complicated gallstone disease, and also plays a main role in...

Burden Of Gallstone Disease

Gallstones are an ancient entity, having occurred more than 3500 years ago according to autopsies performed on Egyptian and Chinese mummies. Gallbladder disease today is a common problem 20 to 25 million Americans harbor gallstones, representing 10 to 15 of the adult population.1 It constitutes a major health burden, with direct plus indirect costs of approximately 6.2 billion annually in the United States.4 This burden has increased more than 20 since the 1980s and accounts for an estimated...