A physiologic imbalance of endocrine function has been recognized in athletes suffering from overtraining. Overtrained athletes often have higher-than-normal concentrations of urea in the blood, which is produced by increased protein catabolism. This is thought to be the mechanism responsible for loss of body weight in overtrained athletes. However, there are no conclusive data to confirm that higher levels of cortisol or epinephrine are related to long periods of overtraining. Serotonin is a major neu-rotransmitter that is believed to play an important role in overtraining syndrome. However, the concentration of serotonin in plasma does not match its concentration in the brain. Cytokines also play a significant role, inasmuch as the presence of circulating cytokines have been associated with trauma related to overtrained muscles, joints, and bones, as well as with infection.
Cytokines appear as part of the body's inflammatory response to injuries and infection. It is believed that excessive musculoskeletal stress, coupled with insufficient rest and recovery, causes local acute inflammation, which eventually evolves into systemic chronic inflammation. Systemic chronic inflammation activates circulating monocytes to synthesize large quantities of cytokines. Cytokine-induced symptoms of sickness are very much consistent with symptoms of overtraining.
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Looked upon as a mysterious practice, reiki originated from Japan, around 1922. Started by a Japanese Buddhist, this practice of purported healing basically uses the palm of an individual to emit positive healing energy unto the patient. Sometimes reiki is referred to as oriental style treatment by professional medical bodies.