Type 2 Diabetes Mellitus

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Type 2 diabetes mellitus is characterized by a genetic predisposition to the disorder, decreased tissue sensitivity to insulin (insulin resistance), and impaired function of pancreatic P-cells, which control the timely release of insulin (Anderson, 1999). Obesity, physical inactivity, and advancing age are primary risk factors for insulin resistance and development of type 2 diabetes (Barrett-Connor, 1989; Colditz et al., 1990; Helmrich et al., 1991; Manson et al., 1991). Dietary factors have also been suggested as playing a major role in the development of insulin resistance and type 2 diabetes.

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