CT has considerable potential as a treatment for depression and related problems in patients with chronic medical illnesses. For most illnesses, however, there is not yet enough evidence from rigorous clinical trials to claim that CT is a safe and efficacious treatment for comorbid depression. It will take years to amass the evidence needed to determine whether CT can truly be called an empirically supported therapy for comorbid depression in patients with chronic medical conditions. For now, clinicians who seek evidence to support the use of CT with medically ill patients have relatively little to draw upon except for ENRICHD, a handful of small comorbid depression trials in various medical populations, and CT trials conducted in generally healthy but depressed patient populations, such as the recent trial by DeRubeis et al. (2005). Several relevant studies are currently in progress, and there is good reason to hope that a number of high-quality trials will be published over the next decade.


We wish to thank Iris Csik, MSW, LCSW, for her comments and suggestions.


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Arthritis Joint Pain

Arthritis Joint Pain

Arthritis is a general term which is commonly associated with a number of painful conditions affecting the joints and bones. The term arthritis literally translates to joint inflammation.

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