Hemorrhagic cystitis (bleeding from the bladder) may result from administration of certain chemotherapy drugs used in your child's conditioning regimen. Occasionally, it is caused by a bacterial or viral bladder infection. Symptoms of hemorrhagic cystitis include blood in the urine (which may be obvious to the eye or microscopic), blood clots in the urine, pain with urination, and bladder discomfort. If your child receives a chemotherapy drug that has the potential to cause this problem, Mesna may be used to decrease the risk of bladder damage due to cyclophosphamide and related drugs. If your child develops hemorrhagic cystitis or a urinary tract infection, she will receive antibiotics, intravenous fluids, and pain medication as needed.
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