Definition of a blast

"Blast" is a short name for an immature white blood cell such as lymphoblast, myeloblast, or monoblast. Normally, less than 5 percent of the cells contained in healthy bone marrow at any one time are blasts. Normal blasts develop into mature, functioning white blood cells, and are not usually found in the bloodstream. Leukemic blasts remain immature, multiply continuously, provide no defense against infection, and may be present in large numbers in the bloodstream and bone marrow.

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