1. Remy JS, et al. Gene transfer with a series of lipophilic DNA-binding molecules. Bioconjug Chem 1994; 5(6):647-54.

2. Clamme JP, et al. Gene transfer by cationic surfactants is essentially limited by the trapping of the surfactant/DNA complexes onto the cell membrane: A fluorescence investigation. Biochim Biophys Acta 2000; 1467(2):347-61.

3. Blessing T, Remy JS, Behr JP. Template oligomerization of cations bound to DNA produces calibrated nanometric particles. J. Am. Chem. Soc 1998; 120:8519-8520.

4. Blessing T, Remy JS, Behr JP. Monomolecular collapse of plasmid DNA into stable virus-like particles. Proc Natl Acad Sci USA 1998; 95(4):1427-31.

5. Dauty E, et al. Dimerizable cationic detergents with a low cmc condense plasmid DNA into nanometric particles and transfect cells in culture. J Am Chem Soc 2001; 123(38):9227-34.

6. Lukacs GL, et al. Size-dependent DNA mobility in cytoplasm and nucleus. J Biol Chem 2000; 275(3):1625-9.

7. Su H, et al. A recombinant Chlamydia trachomatis major outer membrane protein binds to heparan sulfate receptors on epithelial cells. Proc Natl Acad Sci USA 1996; 93(20):11143-8.

8. Summerford C, Samulski RJ. Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions. J Virol 1998; 72(2):1438-45.

9. Behr JP, et al. Efficient gene transfer into mammalian primary endocrine cells with lipopolyamine-coated DNA. Proc Natl Acad Sci USA 1989; 86(18):6982-6.

10. Mislick KA, Baldeschwieler JD. Evidence forthe role of proteo-glycans in cation-mediated gene transfer. Proc Natl Acad Sci USA 1996; 93(22):12349-54.

11. Labat-Moleur F, et al. An electron microscopy study into the mechanism of gene transfer with lipopolyamines. Gene Ther 1996; 3(11):1010-7.

12. Mounkes LC, et al. Proteoglycans mediate cationic liposome-DNA complex-based gene delivery in vitro and in vivo. J Biol Chem 1998; 273(40):26164-70.

13. Freissler E, et al. Syndecan-1 and syndecan-4 can mediate the invasion of OpaHSPG-expressing Neisseria gonorrhoeae into epithelial cells. Cell Microbiol 2000; 2(1):69-82.

14. Dehio C, et al. Ligation of cell surface heparan sulfate proteo-glycans by antibody-coated beads stimulates phagocytic uptake into epithelial cells: A model for cellular invasion by Neisseria gonorrhoeae. Exp Cell Res 1998; 242(2):528-39. Woods A, Couchman JR. Syndecan 4 heparan sulfate proteoglycan is a selectively enriched and widespread focal adhesion component. Mol Biol Cell 1994; 5(2):183-92. Pasqualini R, Koivunen E, Ruoslahti E. Alpha v integrins as receptors for tumor targeting by circulating ligands. Nat Bio-technol 1997; 15(6):542-6.

Hart SL, et al. Integrin-mediated transfection with peptides containing arginine-glycine-aspartic acid domains. Gene Ther 1997; 4(11):1225-30.

Harbottle RP, et al. An RGD-oligolysine peptide: A prototype construct for integrin-mediated gene delivery. Hum Gene Ther 1998; 9(7):1037-47.

Erbacher P, Remy JS, Behr JP. Gene transfer with synthetic virus-like particles via the integrin-mediated endocytosis pathway. Gene Ther 1999; 6(1):138-45.

Suh W, et al. An angiogenic, endothelial-cell-targeted polymeric gene carrier. Mol Ther 2002; 6(5):664-72. Kircheis R, et al. Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic application. Gene Ther 2001; 8(1):28-40. Wolfert MA, et al. Characterization of vectors for gene therapy formed by self-assembly of DNA with synthetic block co-polymers. Hum Gene Ther 1996; 7(17):2123-33. Erbacher P, et al. Transfection and physical properties of various saccharide, poly(ethylene glycol), and antibody-deriva-tized polyethylenimines (PEI). J Gene Med 1999; 1(3):210-22. Vinogradov S, et al. Polyion complex micelles with protein-modified corona for receptor-mediated delivery of oligonucleotides into cells. Bioconjug Chem 1999; 10(5):851-60. Kataoka K, Harada A, Nagasaki Y. Block copolymer micelles for drug delivery: Design, characterization and biological significance. Adv Drug Deliv Rev 2001; 47(1):113-31. Petersen H, et al. Polyethylenimine-graft-poly(ethylene glycol) copolymers: Influence of copolymer block structure on DNA complexation and biological activities as gene delivery system. Bioconjug Chem 2002; 13(4):845-54.

Fisher KD, et al. A versatile system for receptor-mediated gene delivery permits increased entry of DNA into target cells, enhanced delivery to the nucleus and elevated rates of transgene expression. Gene Ther 2000; 7(15):1337-43. Blessing T, et al. Different strategies for formation of pegylated egf-conjugated PEI/DNA complexes for targeted gene delivery. Bioconjug Chem 2001; 12(4):529-37.

Lee H, Jeong JH, Park TG. A new gene delivery formulation of polyethylenimine/DNA complexes coated with PEG conjugated fusogenic peptide. J Control Release 2001; 76(1-2):183-92. Dauty E, et al. Intracellular delivery of nanometric DNA particles via the folate receptor. Bioconjug Chem 2002; 13(4): 831-9.

Zuber G, et al. Targeted gene delivery to cancer cells: Directed assembly of nanometric DNA particles coated with folic acid, submitted.

Reddy JA. Optimization of folate-conjugated liposomal vectors for folate receptor-mediated gene therapy. J Pharm Sci 1999; 88(11):1112-8.

Lin AJ. Structure and structure-function studies of lipid/plasmid DNA complexes. J Drug Target 2000; 8(1):13-27. Zelphati O, Szoka FC. Mechanism of oligonucleotide release from cationic liposomes. Proc Natl Acad Sci USA 1996; 93(21): 11493-8.

Demeneix B. Gene transfer with lipospermines and polyethy-lenimines. Adv Drug Deliv Rev 1998; 30(1-3):85-95. Haensler J, Szoka FC. Polyamidoamine cascade polymers mediate efficient transfection of cells in culture. Bioconjug Chem 1993; 4(5):372-9.

37. Kukowska-Latallo JF. Efficient transfer of genetic material into mammalian cells using Starburst polyamidoamine dendrimers. Proc Natl Acad Sci USA 1996; 93(10):4897-902.

38. Boussif O, et al. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine. Proc Natl Acad Sci USA 1995; 92(16):7297-301.

39. Forrest ML, Pack DW. On the kinetics of polyplex endocytic trafficking: Implications for gene delivery vector design. Mol Ther 2002; 6(1):57-66.

40. Fajac I, et al. Histidylated polylysine as a synthetic vector for gene transfer into immortalized cystic fibrosis airway surface and airway gland serous cells. J Gene Med 2000; 2(5):368-78.

41. Putnam D, et al. Polymer-based gene delivery with low cytotoxicity by a unique balance of side-chain termini. Proc Natl Acad Sci USA 2001; 98(3):1200-5.

42. Han S, Mahato RI, Kim SW. Water-soluble lipopolymer for gene delivery. Bioconjug Chem 2001; 12(3):337-45.

43. Kichler A, et al. Polyethylenimine-mediated gene delivery: A mechanistic study. J Gene Med 2001; 3(2):135-44.

44. Merdan T, et al. Intracellular processing of poly(ethylene imine)/ribozyme complexes can be observed in living cells by using confocal laser scanning microscopy and inhibitor experiments. Pharm Res 2002; 19(2):140-6.

45. Boussif O, Zanta MA, Behr JP. Optimized galenics improve in vitro gene transfer with cationic molecules up to 1000-fold. Gene Ther 1996; 3(12):1074-80.

46. Brunner S, et al. Overcoming the nuclear barrier: Cell cycle independent nonviral gene transfer with linear polyethylenimine or electroporation. Mol Ther 2002; 5(1):80-6.

47. Wightman L, et al. Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivo. J Gene Med 2001; 3(4):362-72.

48. Lisziewicz J, et al. Induction of potent human immunodeficiency virus type 1-specific t-cell-restricted immunity by genetically modified dendritic cells. J Virol 2001; 75(16):7621-8.

49. Dolivet G, et al. In vivo growth inhibitory effect of iterative wild-type p53 gene transfer in human head and neck carcinoma xenografts using glucosylated polyethylenimine nonviral vector. Cancer Gene Ther 2002; 9(8):708-14.

50. Merlin JL, et al. Improvement of nonviral p53 gene transfer in human carcinoma cells using glucosylated polyethylenimine derivatives. Cancer Gene Ther 2001; 8(3):203-10.

51. Aoki K, et al. Polyethylenimine-mediated gene transfer into pancreatic tumor dissemination in the murine peritoneal cavity. Gene Ther 2001; 8(7):508-14.

52. Vernejoul F, et al. Antitumor effect of in vivo somatostatin receptor subtype 2 gene transfer in primary and metastatic pancreatic cancer models. Cancer Res 2002; 62(21):6124-31.

53. Poulain L, et al. Ovarian carcinoma cells are effectively transfected by polyethylenimine (PEI) derivatives. Cancer Gene Ther 2000; 7(4):644-52.

54. Goula a D, et al. Size, diffusibility and transfection performance of linear PEI/DNA complexes in the mouse central nervous system. Gene Ther 1998; 5(5):712-7.

55. Foglieni C, et al. Glomerular filtration is required for transfec-tion of proximal tubular cells in the rat kidney following injection of DNA complexes into the renal artery. Gene Ther 2000; 7(4):279-85.

56. Bragonzi A, et al. Biodistribution and transgene expression with nonviral cationic vector/DNA complexes in the lungs. Gene Ther 2000; 7(20):1753-60.

57. Abdallah Bet al. A powerful nonviral vector for in vivo gene transfer into the adult mammalian brain: Polyethylenimine. Hum Gene Ther 1996; 7(16):1947-54.

58. Guissouma H, et al. Physiological regulation of hypothalamic TRH transcription in vivo is T3 receptor isoform specific. FASEB J 1998; 12(15):1755-64.

59. Guissouma H, et al. Feedback on hypothalamic TRH transcrip- 75. tion is dependent on thyroid hormone receptor N terminus. Mol Endocrinol 2002; 16(7):1652-66.

60. Lemkine G, et al. Optimisation of polyethylenimine-based gene 76. delivery to mouse brain. Drug Target (sous presse) 1999.

61. Lemkine GF, et al. Preferential transfection of adult mouse neural stem cells and their immediate progeny in vivo with poly- 77. ethylenimine. Mol Cell Neurosci 2002; 19(2):165-74.

62. Martres MP, et al. Up- and down-expression of the dopamine 78. transporter by plasmid DNA transfer in the rat brain. Eur J Neurosci 1998; 10(12):3607-16.

63. Pollard H, et al. Polyethylenimine but not cationic lipids pro- 79. motes transgene delivery to the nucleus in mammalian cells. J

Biol Chem 1998; 273(13):7507-11.

64. Pollard H, et al. Ca2 + -sensitive cytosolic nucleases prevent 80. efficient delivery to the nucleus of injected plasmids. J Gene

65. FabreV, et al. Homestatic regulation of serotonergic function by 81. the serotonin transporter as revealed by nonviral gene transfer. J Neurosci 2000; 20(13):5065-75.

66. Wang S, et al. Transgene expression in the brain stem effected by intramuscular injection of polyethylenimine/DNA com- 82.

67. Coen L, et al. Construction of hybrid proteins that migrate retro-gradely and transynaptically into the central nervous system. 83. Proc Natl Acad Sci USA 1997; 94(17):9400-5.

68. Rudolph C, et al. In vivo gene delivery to the lung using polyethylenimine and fractured polyamidoamine dendrimers. J Gene 84. Med 2000; 2(4):269-78.

69. Densmore CL, et al. Aerosol delivery of robust polyethyleneim-ine-DNA complexes for gene therapy and genetic immuniza- 85. tion. Mol Ther 2000; 1(2):180-8.

70. Gautam A, et al. Enhanced gene expression in mouse lung after PEI-DNA aerosol delivery. Mol Ther 2000; 2(1):63-70. 86.

71. Koping-Hoggard M, et al. Chitosan as a nonviral gene delivery system. Structure-property relationships and characteristics compared with polyethylenimine in vitro and after lung admin- 87. istration in vivo. Gene Ther 2001; 8(14):1108-21.

72. Goula b D, et al. Polyethylenimine-based intravenous delivery of transgenes to mouse lung. Gene Ther 1998; 5(9):1291-5.

73. Zou SM, et al. Systemic linear polyethylenimine (L-PEI)- 88. mediated gene delivery in the mouse. J Gene Med 2000; 2(2): 128-34.

74. Goula D, et al. Rapid crossing of the pulmonary endothelial 89. barrier by polyethylenimine/DNA complexes. Gene Ther 2000; 7(6):499-504.

Kircheis R, et al. Tumor targeting with surface-shielded li-gand-polycation DNA complexes. J Control Release 2001; 72(1-3):165-70.

Coll JL, et al. In vivo delivery to tumors of DNA complexed with linear polyethylenimine. Hum Gene Ther 1999; 10(10): 1659-66.

Zabner J, et al. Cellular and molecular barriers to gene transfer by a cationic lipid. J Biol Chem 1995; 270(32):18997-9007. Andreadis S, Fuller AO, Palsson BO. Cell cycle dependence of retroviral transduction: An issue of overlapping time scales. Biotechnol Bioeng 1998; 58(2-3):272-81. Brunner S, et al. Cell cycle dependence of gene transfer by lipoplex, polyplex and recombinant adenovirus. Gene Ther 2000; 7(5):401-7.

Horbinski C, et al. Polyethyleneimine-mediated transfection of cultured postmitotic neurons from rat sympathetic ganglia and adult human retina. BMC Neurosci 2001; 2(1):2. Remy JS, et al. Targeted gene transfer into hepatoma cells with lipopolyamine-condensed DNA particles presenting galactose ligands: A stage toward artificial viruses. Proc Natl Acad Sci USA 1995; 92(5):1744-8.

Sebestyen MG, et al. DNA vector chemistry: The covalent attachment of signal peptides to plasmid DNA. Nat Biotechnol 1998; 16(1):80-5.

Ludtke JJ, et al. A nuclear localization signal can enhance both the nuclear transport and expression of 1 kb DNA. J Cell Sci 1999; 112(Pt 12):2033-41.

Neves C, et al. Coupling of a targeting peptide to plasmid DNA by covalent triple helix formation. FEBS Lett 1999; 453(1-2): 41-5.

Ciolina C, et al. Coupling of nuclear localization signals to plasmid DNA and specific interaction of the conjugates with importin alpha. Bioconjug Chem 1999; 10(1):49-55. Branden LJ, Mohamed AJ, Smith CI. A peptide nucleic acid-nuclear localization signal fusion that mediates nuclear transport of DNA. Nat Biotechnol 1999; 17(8):784-7. Zanta MA, Belguise-Valladier P, Behr JP. Gene delivery: A single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus. Proc Natl Acad Sci USA 1999; 96(1): 91-6.

Rolland AP. From genes to gene medicines: Recent advances in nonviral gene delivery. Crit Rev Ther Drug Carrier Syst 1998; 15(2):143-98.

Nishikawa M, Huang L. Nonviral vectors in the new millennium: Delivery barriers in gene transfer. Hum Gene Ther 2001; 12(8):861-70.

10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

Get My Free Ebook

Post a comment