McGee LH, Abel H, Hauswirth WW, Flannery JG. Glial cell line derived neurotrophic factor delays photoreceptor degeneration in a transgenic rat model of retinitis pigmentosa. Mol Therapy 2001; 4:622-629.

Bok D, Yasumura D, Matthes MT, Ruiz A, Duncan JL, Chappelow AV, Zolutukhin S, Hauswirth W, LaVail MM. Effects of adeno-associated virus-vectored ciliary neuro-trophic factor on retinal structure and function in mice with a P216L rds/peripherin mutation. Exp Eye Res 2002; 74: 719-735.

Lewin AS, KA Drenser, WW Hauswirth, S Nishikawa, D Ya-sumura, JG Flannery, LaVail MM. Ribozyme rescue of photoreceptor cells in a transgenic model of autosomal dominant retinitis pigmentosa. Nat Med 1998; 4:967-971. Ali RR, Sarra GM, Stephens C, Alwis MD, Bainbridge JW, Munro PM, Fauser S, Reichel MB, Kinnon C, Hunt DM, Bhattacharya SS, Thrasher AJ. Restoration of photoreceptor ultrastructure and function in retinal degeneration slow mice by gene therapy. Nat Genet 2000; 25:306-310. Raisler BJ, Berns KI, Grant MB, Beliaev D, Hauswirth WW. Adeno-associated virus type-2 expression of pigmented epithelium-derived factor or Kringles 1-3 of angiostatin reduce retinal neovascularization. Proc Natl Acad Sci USA 2002; 99: 8909-8914.

Mori K, Gehlbach P, Yamamoto S, Duh E, Zack DJ, Li Q, Berns KI, Raisler BJ, Hauswirth WW, Campochiaro PA. AAV-mediated gene transfer of pigment epithelium-derived factor inhibits choroidal neovascularization. Invest Ophthal-mol Vis Sci 2002; 43:1994-2000.

Bainbridge JW, Mistry A, De Alwis M, Paleolog E, Baker A, Thrasher AJ, Ali RR. Inhibition of retinal neovascularisation by gene transfer of soluble VEGF receptor sFlt-1. Gene Ther 2002; 9:320-326.

Lai YK, Shen WY, Brankov M, Lai CM, Constable IJ, Ra-koczy PE. Potential long-term inhibition of ocular neovascu-larisation by recombinant adeno-associated virus-mediated secretion gene therapy. Gene Ther 2002; 9:804-813. Acland GM, Aguirre GD, Ray J, Zhang Q, Aleman TS, Cideci-yan AV, Pearce-Kelling SE, Anand V, Zeng Y, Maguire AM, Jacobson SG, Hauswirth WW, Bennett J. Gene therapy restores vision in a canine model of childhood blindness. Nat Genet 2001; 28:92-95.

Harris EJ. Rheumatoid arthritis. Pathophysiology and implications for therapy. New Engl J Med 1990; 322:1277-1289. Brennan FM, Feldman M. Cytokines in autoimmunity. Curr Opin Immunol 1992; 4:754-759.

Arend WP, Dayer JM. Inhibition of the production and effects of interleukin-1 and tumor necrosis factor a in rheumatoid arthritis. Arthritis Rheum 1995; 38:151-160. Watanabe S, Imagawa T, Boivin GP, Gao G, Wilson JM, Hirsch R. Adeno-associated virus mediates long-term gene transfer and delivery of chondroprotective IL-4 to murine sy-novium. Mol Ther 2002; 2:147-152.

Cottard V, Mulleman D, Bouille P, Mezzina M, Boissier MC, Bessis N. Adeno-associated virus-mediated delivery of IL-4 prevents collagen-induced arthritis. Gene Ther 2000; 7: 1930-1939.

Apparailly F, Millet V, Noel D, Jacquet C, Sany J, Jorgensen C. Tetracycline-inducible interleukin-10 gene transfer mediated by an adeno-associated virus: Application to experimental arthritis. Hum Gene Ther 2002; 13:1179-1188. Zhang HG, Xie J, Yang P, Wang Y, Xu L, Liu D, Hsu HC, Zhou T, Edwards CK, Mountz JD. Adeno-associated virus production of tumor necrosis factor receptor neutralizes tumor necrosis factor alpha and reduces arthritis. Hum Gene Ther 2000; 11:2431-2442.

277. Chan JMK, Jin WW, Stepan T, Burstein H, Wahl SM. Suppression of SCW-induced arthritis with recombinant TNFR:Fc gene transfer. Mol Ther 2002; 6:1-10. 287.

278. Pan RY, Chen SL, Xiao X, Liu DW, Peng HJ, Tsao YP. Therapy and prevention of arthritis by recombinant adeno-associ-ated virus vector with delivery of interleukin-1 receptor antag- 288. onist. Arthritis Rheum 2000; 43:289-297.

279. Yew NS, Cheng SH. Gene therapy for lysosomal storage diseases. Curr Opin Mol Ther 2002; 3:399-406.

280. Daly TM, Vogler C, Levy B, Haskins ME, Sands MS. Neonatal gene transfer leads to widespread correction of pathology in a murine model of lysosomal storage disease. Proc Natl 289. Acad Sci USA 1999; 96:2296-2300.

281. Daly TM, Okuyama T, Vogler C, Haskins ME, Muzyczka N, Sands MS. Neonatal intramuscular injection with recombinant Adeno-associated virus results in prolonged ß-glucuronidase 290. expression in situ and correction of liver pathology in mucopolysaccharidosis type VII mice. Hum Gene Ther 1999; 10: 85-94.

282. Sferra TJ, Qu G, McNeely D, Rennard R, Clark KR, Lo WD, 291. Johnson PR. Recombinant adeno-associated virus-mediated correction of lysosomal storage disease within the central nervous system of the adult mucopolysaccharidosis type VII mouse. Hum Gene Ther 2000; 11:507-519. 292.

283. Elliger S, Elliger CA, Lang C, Watson GL. Enhanced secretion and uptake of ß-glucuronidase improves adeno-associated viral-mediated gene therapy of mucopolysaccharidosis type VII in mice. Mol Ther 2002; 5:617-626.

284. Frisella WA, O'Connor LH, Vogler CA, Roberts M, Walkley S, Levy B, Daly TM, Sands MS. Intracranial injection of re- 293. combinant adeno-associated virus improves cognitive function in a murine model of mucopolysaccharidosis type VII. Mol Ther 2001; 3:351-358.

285. Jung SC, Han IP, Limaye A, Xu R, Gelderman MP, Zerfas P, Tirumalai K, Murray GJ, During MJ, Brady RO, Qasba P. Adeno-associated viral vector-mediated gene transfer results 294. in long-term enzymatic and functional correction in multiple organs of Fabry mice. Proc Natl Acad Sci USA 2001; 98: 2676-2681. 295.

286. Fraites TJ, Schlessing MR, Shanely RA, Walter GA, Cloutier DA, Zolotukhin I, Pauly DF, Raben N, Plotz PH, Powers SK, Kessler PD, Byrne BJ. Correction of the enzymatic and func-

tional deficits in a model of Pompe disease using adeno-associ-

ated virus vectors. Mol Ther 2002; 5:571-578.

Clark KR, Sferra TJ, Johnson PR. Recombinant adeno-associ-

ated viral vectors mediate long-term transgene expression in muscle. Hum Gene Ther 1997; 8:659-669.

Herzog RW, Yang EY, Couto LB, Hagstrom JN, Elwell D,

Fields PA, Burton M, Bellinger DA, Read MS, Brinkhous KM,

Podsakoff GM, Nichols TC, Kurtzman GJ, High KA. Long-

term correction of canine hemophilia B by gene transfer of blood coagulation factor IX mediated by adeno-associated viral vector. Nat Med 1999; 5:56-63.

Zhang Y, Chirmule N, Gao G, Wilson JM. CD40 ligand-de-

pendent activation of cytotoxic T lymphocytes by adeno-asso-

ciated virus vectors in vivo: role of immature dendritic cells.

J Virol 2000; 74:8003-8010.

Sarukhan A, Soudais C, Danos O, Jooss K. Factors influencing cross-presentation of non-self antigens expressed from recombinant adeno-associated virus vectors. J Gene Med 2001; 3: 260-270.

Sarukhan A, Camugli S, Gjata B, von Boehmer H, Danos O, Jooss K. Successful interference with cellular immune responses to immunogenic proteins encoded by recombinant viral vectors. J Virol 2001; 75:269-277. Xin KQ, Urabe M, Yang J, Nomiyama K, Mizukami H, Ha-majima K, Nomiyama H, Saito T, Imai M, Monahan J, Okuda K, Ozawa K, Okuda K. A novel recombinant adeno-associated virus vaccine induces a long-term humoral immune response to human immunodeficiency virus. Hum Gene Ther 2001; 12: 1047-1061.

Xin KQ, Ooki T, Mizukami H, Hamajima K, Okudela K, Hashimoto K, Kojima Y, Jounai N, Kumamoto Y, Sasaki S, Klin-man D, Ozawa K, Okuda K. Oral administration of recombinant adeno-associated virus elicits human immunodeficiency virus-specific immune responses. Hum Gene Ther 2002; 13: 1571-1581.

Johnson PR, Schnepp BC, Montefiori DC, Letvin NL, Clark KR. Novel SIV/HIV vaccines based on recombinant adeno-associated virus vectors. Mol Ther 2001; 23:S15-S16. Liu DW, Tsao YP, Kung JT, Ding YA, Sytwu HK, Xiao X, Chen SL. Recombinant adeno-associated virus expressing human papillomavirus type 16 E7 peptide DNA fused with heat shock protein DNA as a potential vaccine for cervical cancer. J Virol 2000; 74:2888-2894.

Arthritis Relief Now

Arthritis Relief Now

When you hear the word arthritis, images of painful hands and joints comes into play. Few people fully understand arthritis and this guide is dedicated to anyone suffering with this chronic condition and wants relief now.

Get My Free Ebook

Post a comment