Effective management of the consequences and sequelae of cancer diagnosis and treatment is becoming more important as the number of cancer survivors has become a top priority of health care. Certain symptoms are common after cancer treatment. We have grouped these into four categories for the purposes of this chapter. These include: (1) Symptoms of distress; (2) Problems relating to sleep difficulties and persistent fatigue; (3) Existential and spiritual issues, and; (4) Persistent underlying biological changes that may result in increased risk for other diseases or cancer recurrence. Each area will be summarized but not reviewed exhaustively.

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