The life-altering burden of cancer has frame shifted from a narrow focus on the direct effects of anti-cancer therapy and overall survival to a spectrum of medical and nonmedical issues termed cancer survivorship. Survivorship still includes "traditional" consequences such as short- and long-term treatment side-effects and the development of second cancers.1-3 In addition, cancer survivorship includes "newly" recognized psychological and psychosocial perturbations.4-7 For many patients, the latter issues are more challenging than the defined course of direct anti-cancer therapy. These "new" responsibilities represent a formidable management challenge for physicians and the health care community.

Cancer medicine has become a paradigm of treatment success with the identification of causative factors, most notably genetic abnormalities, and the evolution of therapy from nonselective cytotoxic agents to biochemically defined targeted therapy. Currently, greater than 60% and 80%, respectively, of all adult and childhood cancer patients will survive more than 5 years after their initial diagnosis. Improved treatment, by eliminating debilitating toxicity and the inevitability of rapid demise, facilitated the realization that patients require the totality of survivorship care.

The medical literature notes that cancer patients suffer from the physical consequences of their disease, the adverse events from anti-cancer therapy, and the emotional toll than remain well after the completion of anti-cancer therapy.8 This chapter will review the burden of cancer survivorship using a recently conducted cancer survivorship survey that elucidated areas of concern for patients. Data presented will also demonstrate that cancer survivorship is increasing and is a largely unmet responsibility of health care providers.

Reports of cancer survivorship needs and broad-based far-reaching recommendations have been presented by the National Institutes of Health Office for Cancer Survivorship, the Centers for Disease Control with the Lance Armstrong Foundation (LAF), and the Institutes of Medicine.9-12 These proposals outline a plan for identifying, studying, and managing the spectrum of issues of cancer survivorship.

10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

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