Sarcoid is a multisystem disorder characterized by non-caseating granuloma. There seems to be two overlapping patterns of clinical presentation in the juvenile population with skin, joint and eye disease in younger children, and lymphadenopathy, weight loss, fever, pulmonary involvement, but no arthritis, in older children and adolescents (42). Sarcoid is more common in the black population and females. Treatment is with steroids and a steroid sparing agent such as methotrexate or azathioprine.
In a study of 1784 Turkish patients with Behcet's disease (BD), 95 were less than 16 years old, most of whom were between 10 and 16 years of age (43). The diagnostic criteria developed by the International Study Group are most widely used to define BD (44). This requires the presence of recurrent oral ulceration and two of: recurrent genital ulceration, eye lesions, skin lesions, and pathergy. There are no features of BD that are specific to age-of-onset although the psychological impact of significant genital ulceration during adolescence and the development of a sexual identity should not be underestimated.
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