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The number of analgesics and interventions used is a sign that there are no well controlled therapeutic trials in the arena of childhood chronic pain. It is becoming widely accepted, however, that any analgesic intervention should be alongside multidisciplinary therapy (58-61). It is unusual for analgesia to work alone.

Oral treatments that have been used, with variable success, include tricyclic antidepressants, nonsteroidals, opioids, anticonvulsants and glucocorticoids (62,63). Sympathetic blocks (64), TENS (23) and botulinum injections have been used in localized pain (62). In some centers spinal stimulation are also advocated. Complementary therapies are commonly utilized by patients with chronic pain (65). The evidence supporting many of these therapies in children and adolescents is poor (66) but many young adults find certain therapies such as acupuncture, massage and aromatherapy helpful.

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