Nonadherence is a complex health-related problem that is influenced by multiple factors. The World Health Organization report on nonadherence (8) identified five interrelated, but distinct categories of risk factors for non-adherence with medication taking: socioeconomic factors, patient-related factors, condition-related factors, treatment-related factors, and factors related to the health care system and health care team. These categories can also be used to classify risk factors to adherence with non-pharmacological aspects of treatment. The following paragraphs summarize the evidence on risk factors in patients with JIA, while also providing relevant information found in other populations with chronic illness as well. Table 1 provides an overview of potential risk-factors for poor adherence.
Overall, most evidence is available for risk factors for poor medication adherence. Risk factors for poor adherence to exercise, orthopedic or appointment-keeping are less well documented.
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