Thomas F Babor Revised by Amy Loerch Strumolo

DIAGNOSTIC INTERVIEW SCHEDULE (DIS) Developed in the late 1970s for use in large-scale studies of the prevalence of mental disorders in the U.S. population (Regier et al., 1984), the Diagnostic Interview Schedule (DIS) is a highly structured psychiatric interview that carefully specifies the questions that the interviewer must ask to make a DIAGNOSIS. Another version is the DISC, or Diagnostic Interview Schedule for Children. Unlike the DIS, this version allows the re-ordering of questions or sections. Because the DIS requires a minimum of clinical judgment, it can be administered by nonprofessional or nonclinician interviewers who have received a week of intensive training. In addition to alcohol and other substance-use disorders, the DIS provides diagnostic information about DEPRESSION, SCHIZOPHRENIA, and Anxiety disorders; eating disorders; Anti-social Personality; and a variety of other psychiatric conditions. The DIS has been the subject of a number of validation studies showing that nonclinician interviewers diagnose patients as accurately as trained clinicians using criteria from DSM-III (Diagnostic and Statistical Manual of Mental Disorders, third edition). With the American Psychiatric Association's publication of the revised versions of DSM, major changes were made to the DIS as well.

In June 2000 a study of 349 individuals who were given the DIS was published, then examined by psychiatrists using the Schedules for Clinical Assessment in Neuropsychiatry (SCAN). The DIS missed many cases of major depressive disorders (as determined by SCAN), but there was correlation in the symptom groups. The researchers concluded that DIS may be too conservative with risk factors.

The DIS was first used in The Epidemiologic Catchment Area (ECA) study, which was a survey of mental disorders in the United States. This survey's results led to worldwide testing, which in turn led to comparative analyses among the nations.

The DIS also has been widely used in research on substance-use disorders (Helzer & Canino, 1992), in part because it can be administered by nonclinician interviewers in population surveys. Interviewers read questions aloud to the subject exactly as they are written in the interview booklet. No deviation from the written format is allowed, except to repeat questions that may have been misunderstood. A set of standard probes is used to determine whether a given symptom was caused by the effects of physical illness. The interviewer also asks for the age of onset and the recency of most symptoms.

A series of thirty questions constitutes the ALCOHOL DEPENDENCE/abuse section of the DIS. The section begins with questions about alcohol consumption and intoxication (e.g., ''Have you ever gone on binges or benders where you kept drinking for a couple of days or more without sobering up?''). Additional questions are asked to diagnose the symptoms of dependence (e.g., ''Did you ever get tolerant to alcohol, that is, you needed to drink a lot more in order to get an effect, or found that you could no longer get high on the amount you used to drink?''). A third type of question pertains to the symptoms of alcohol abuse (e.g., ''Have you ever had trouble driving because of drinking—like having an ACCIDENT or being arrested for drunk driving?'').

The drug dependence section of the DIS (version III-B) consists of twenty-four questions that conform to the DSM-III-R criteria for drug use disorders. This section begins by asking if the patient has used any of the following types of drugs ''to get high or for other mental effects'': MARIJUANA,

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