Summary And Conclusion

In this paper, major issues related to drug testing are discussed. For example, drug-testing techniques measure drug presence but are not sophisticated enough to measure impairment from drug use. It is also very difficult to determine the route of drug administration, quantity, frequency, or when the drug was last taken.

Selection of the drug to be tested should depend on the local availability of the drug, its abuse potential, and clinical effects, as well as the available analytical technology and expertise in testing and interpretation of the laboratory results. The most sophisticated drug-testing approach, gas chroma-tography in combination with mass spectrometry, is considered as a gold standard and thus utilized in confirmatory testing. Typically GC/MS is preceded by a rapid immunoassay method to eliminate the majority of negative samples.

Despite the existence of sophisticated drug-testing methods, incorrect test results can still occur. These can be due to the presence of interfering substances or adulteration of the urine sample. Patients have been known to adulterate urine samples to avoid drug detection. A number of techniques can be employed to reduce the likelihood of obtaining erroneous results, as well as detect adulterated urine samples. [Parana ''positive'' drug finding can have a serious impact on the livelihood of an individual, therefore the performance of these tests should adhere to the strictest laboratory standards of performance. Only qualified and experienced individuals with proper laboratory equipment should perform these analyses. Standards of laboratory performance must meet local legal and forensic requirements. Access to the patient samples as well as laboratory records must be restricted in order to prevent tampering of samples and results. To maintain confidentiality and assure proper interpretation of results, the results must be communicated only to the physician reviewing the case/patient. Chain of custody and all documents pertaining to the urine sample must be maintained so that they can be examined in case of a legal challenge. Laboratory must have a complete record on quality control. Finally, specific initial and confirmatory testing requirements should be met.

BhushanM. Kapur

Drug Free Life

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