Malcolm H Lader

BENZOYLECOGNINE Cocaine is metabolized by plasma and liver enzymes (cholinesterases) to water-soluble metabolites that are excreted in the urine. The two major metabolites are ben-zoylecognine and ecognine methyl ester, with only benzoylecognine reported to have behavioral activity. Since COCAINE has a relatively short half-life and may only be present in the urine for twenty-four to thirty-six hours, benzoylecognine levels in urine are useful markers of cocaine use, because it

Figure 1

Benzoylecognine

Figure 1

Benzoylecognine is present for a longer time in urine, two to four days, depending on the quantity of cocaine ingested. Assays for this metabolite are frequently employed in treatment programs, to evaluate compliance with the program, and in workplace drug testing to indicate cocaine use. Under these conditions, it is important to keep in mind that ben-zoylecognine in the urine is an indication of prior cocaine use, but reflects neither current use nor impairment.

(SEE ALSO: Cocaethylene; Drug Testing andAnaly-sis)

Drug Addiction

Drug Addiction

If you're wanting to learn about drug addiction... Then this may be the most important letter you'll ever read You Are Going To Get A In Depth Look At One Of The Most Noteworthy Guides On Drug Addiction There Is Available On The Market Today. It Doesn't Matter If You Are Just For The First Time Looking For Answers On Drug Addiction, This Guide Will Get You On The Right Track.

Get My Free Ebook


Post a comment