Jim Baumohl

HONG KONG AND DRUGS See Opioids and Opioid Control: History of

HYDROMORPHONE Hydromorphone is a semisynthetic OPIOID analgesic (painkiller) derived from thebaine, an ALKALOID of the OPIUM poppy (PAPAVER SOMNIFERUM). It is one of the most widely used and effective analgesics for moderate to severe PAIN and is often referred to as Dilaudid, one of the brand names under which it is sold. Its potency is almost eightfold greater than is morphine's. Structurally, it is quite similar to MOR

PHINE but most like dihydromorphine, differing only in the replacement of the hydroxyl (—0H) group at the 6-position with a ketone ( = 0). Thus, it is not surprising that hydromorphone has many of the same side effects—including sedation, constipation, and depression of breathing. Chronic use will produce TOLERANCE AND PHYSICAL DEPENDENCE, much like morphine. This drug is reported to have high abuse potential, perhaps due, in part, to its very high potency.

Figure 1



JAFFE, J. H., & MARTIN, W. R. (1990). Opioid analgesics and antagonists. In A. G. Gilman et al. (Eds.), Goodman and Gilman's the pharmacological basis of therapeutics, 8th ed. New York: Pergamon.

Drug Addiction

Drug Addiction

If you're wanting to learn about drug addiction... Then this may be the most important letter you'll ever read You Are Going To Get A In Depth Look At One Of The Most Noteworthy Guides On Drug Addiction There Is Available On The Market Today. It Doesn't Matter If You Are Just For The First Time Looking For Answers On Drug Addiction, This Guide Will Get You On The Right Track.

Get My Free Ebook

Post a comment