Complications Due To Ingestion

Ingestion is the way ALCOHOL, liquid medicines, pills and capsules are usually taken. Ingested drugs enter the gastrointestinal (GI) system, undergo some digestive processing, and enter the bloodstream through the walls of the stomach and intestines. Most medical complications from drug ingestion are a result of the corrosive and irritant effects of the drugs on the GI system. Alcohol and a variety of medicines, including aspirin, can cause intense, localized irritation to the GI mucous membranes, leading to ulceration and GI bleeding. Pharmaceutical manufacturers attempt to decrease the danger of GI irritation by adding buffers to their pills and capsules. Buffers are inert or nonactive ingredients that cushion the corrosive effect of the active ingredients. However, if drug users attempt to dissolve pills intended for oral use and inject them, these buffers will often cause problems, such as abscesses or embolisms.

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