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BENZENE See Inhalants

BENZODIAZEPINES The benzodiazepines were introduced into clinical practice in the 1960s for the treatment of anxiety and sleep disorders. Members of this class of drug were classified initially as minor tranquilizers although this term has fallen into disfavor. These agents have proven to be safe and effective alternatives to older SEDATIVE-HYPNOTIC agents such as BARBITURATES, CHLORAL HYDRATE, glutethimide, and carbamates. Benzodiazepines are widely prescribed drugs, with 8.3 percent of the U.S. population reporting medical use of these agents in 1990.

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