Antialcohol Drugs

This category generally covers both drugs used to diminish motivation for drinking plus those that cancel (as antagonists) alcohol intoxication. Although the list of possible antagonists is long—and includes AMPHETAMINES and CAFFEINE—no convincing antagonism has been documented. Therefore, no pharmacological agent exists to cancel out the psychomotor effects of alcohol to allow sober performance.

(SEE ALSO: Accidents and Injuries from Alcohol; Addiction: Concepts and Definitions; Blood Alcohol Concentration; Driving, Alcohol, and Drugs; Driving Under the Influence; Drunk Driving)


Dorian, P., et al. (1983). Amitriptyline and ethanol: Pharmacokinetic and pharmacodynamic interaction. European Journal of Clinical Pharmacology, 25, 325-331.

Mattila, M.J. (1990). Alcohol and drug interactions.

Annals of Medicine, 22, 363-369. Moscowitz, H. (1984). Attention tasks as skilled performance measures of drug effect. British Journal of Clinical Pharmacology, 18, 51S-61S. O'Hanlon, J. F. & deGier, J. J. (Eds.). (1986). Drugs and driving, London: Taylor & Francis. Starmer, G. A., & Bird, K. D. (1984). Investigating drug-ethanol interactions. British Journal of Clinical Pharmacology, 18, 27S-35S.


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